AIC Application

Metabolic & Cellular Health

Ionic calcium, the active form of calcium in the blood, is essential for regulating insulin sensitivity and hormone secretion, which are key factors in managing metabolic syndrome.

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Photo: fingertip with blood drop next to glucose meter test strip. AIC IONIC CALCIUM THERAPY : Metabolic Syndrome
Background: blurred photo of a crowd of people. DIABETES STATISTICS According to WHO, the global prevalence of diabetes was estimated to be 9% among adults aged 18+ years 371 million people have diabetes in the world and 4 million deaths were caused by diabetes in 2011 WHO projects that diabetes will be the 7th leading cause of death in 2030 $471 billion was spent treating diabetes in 2012.
ADA (American Diabetes Association) Website Research “Increased Serum Calcium Levels and Risk of Type 2 Diabetes in Individuals at High Cardiovascular Risk”
CALCIUM AND DIABETES Blood Glucose Green up arrows. + Insulin Green up arrows. + Blood Glucose Red down arrows. Regulates In diabetes, the beta cells can no longer produce enough insulin to overcome insulin resistance, causing blood glucose levels to rise above the normal range Ca²⁺ Intracellular messenger New studies show that calcium ion is needed for the release of insulin to respond to higher amounts of blood glucose and also to reduce insulin resistance
AIC’s Effect on DIABETES Ca²⁺ homeostasis impaired Arrow. High serum calcium concentration Arrow. Increased Insulin Resistance Arrow. Type 2 diabetes with AIC Calcium (double benefits) Ca²⁺ Lowers serum calcium concentration by increasing BMD Red down arrows. Green up arrows. Increases Insulin Sensitivity Ca²⁺ Pancreas Regulates Insulin Red down arrows. Lowers blood glucose
Screenshot of a journal article first page; black panel with hexagon outlines at right. IOSR Journal of Dental and Medical Sciences (IOSR-JDMS) e-ISSN: 2279-0853, p-ISSN: 2279-0861.Volume 13, Issue 8 Ver. II (Aug. 2014), PP 01-03 www.iosrjournals.org Serum Calcium Levels In Type 2 Diabetes Mellitus Kanchana. N¹, Saikumar. P² ¹-Department of physiology / Sree Balaji Medical College, Bharath University, Chennai India / Second year Physiology PG ²- Department of physiology / Sree Balaji Medical College, Bharath University, Chennai India / Professor and HOD Abstract:
Screenshot of a PubMed abstract page on blue background. Diabet Med. 2009 Mar;26(3):211-9. doi: 10.1111/j.1464-5491.2009.02673.x. Insulin sensitivity increase after calcium supplementation and change in intraplatelet calcium and sodium-hydrogen exchange in hypertensive patients with Type 2 diabetes. Pikilidou MI¹, Lasaridis AN, Sarafidis PA, Befani CD, Koliakos GG, Tziolas IM, Kazakos KA, Yovos JG, Nilsson PM. ⊕ Author information Abstract PMID: 19317814 DOI: 10.1111/j.1464-5491.2009.02673.x
Screenshot of a PubMed abstract page. J Physiol Pharmacol. 2008 Dec;59 Suppl 6:219-29. The influence of insulin on calcium ion concentration during transduction of signals into neutrophils. Demkow U¹, Winklewski P, Potapinska O, Popko K, Lipinska A, Wasik M. ⊕ Author information Abstract PMID: 19218646
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AIC AND BONE METABOLISM INDEX IN ANIMAL TRIAL Osteoporosis was completely reversed with AIC Therapy. Osteocalcin, estradiol, eosinophil, CTx, BMD levels were all elevated with AIC Therapy. Estradiol (pg/mL) Osteocalcin (ng/mL) C-terminal telopeptide (ng/mL) BMD Control 4.536±0.343 ᵃ 3.398±0.294 ᵃ 4.751±0.244 ᵃ 0.2276±0.011 ᵃ OVX 3.920±0.277 ᵃ 4.047±0.501ᵇᵇ 5.082±0.462 ᵃᵇ 0.1965±0.012 ᵇ OVX + AIC 4.217±0.247 ᵃ 3.558±0.154 ᵃᶜ 4.360±0.495 ᵃ 0.2276±0.012 ᵃ Osteocalcin column outlined with a dark blue box. Effects of Antiorbital Ionic Molecule Calcium Carbonate on bone turnover and calcium balance in ovariectomized rats. Values are mean ± SD for 5 rats. Means with different superscript letters are significantly different at p<0.05 by Duncan’s multiple range tests. Control: sham operation OVX: no treatment after ovariectomy OVX+AIC: AIC Therapy after ovariectomy. (Lab Anim Res 2011: 27(4), 301-307, 2011)
Diabetes & Bone Health Screenshot of a journal article first page. Observational Study Medicine OPEN Associations between bone-alkaline phosphatase and bone mineral density in adults with and without diabetes Hailing Chen, PhD*, Jufen Li, PhD, Qian Wang, MD Abstract Abbreviations: A1C = hemoglobin A1C, BAP = bone alkaline phosphatase, BMD = bone mineral density, DM = diabetes mellitus, DXA = dual-energy x-ray absorptiometry, MET = metabolic equivalents of task, MetS = metabolic syndrome. Keywords: bone alkaline phosphatase, bone mineral density, diabetes, glycohemoglobin Introduction
BONE AS AN ENDOCRINE ORGAN A genetics approach has uncovered that bone has more functions than expected. In particular, bone is an endocrine organ that secretes a growing number of hormones. In that context, the discovery of the osteoblast-derived hormone osteocalcin has significantly broadened the field of bone biology because of the number of physiologic processes regulated by this hormone. At present, osteocalcin has been shown to enhance several aspects of energy metabolism, brain development, and cognition. These discoveries shed light on the cross-talk between multiple organs and provide credence to the search for additional endocrine functions of bone.
Functions of Osteocalcin Diagram: bone sending osteocalcin to pancreas, brain, muscle, fat, testes. Insulin Osteocalcin Pancreas ↑ Insulin synthesis ↑ β-cell proliferation Brain ↑ Neurotransmitter Production Muscle ↑ Insulin sensitivity Adipose ↑ Insulin sensitivity ↑ Adiponectin ↓ Fat mass Testes ↑ Testosterone Diagram: osteocalcin and adiponectin pathways. Osteoblast Ocn Gene ↓ Osteocalcin Bone Osteocalcin uncarboxylated + Pancreas Increased β-cell proliferation Increased insulin secretion Adipocyte + Adiponectin (insulin-sensitizing adipokine) Muscles +
Screenshot of a newspaper web article, shown tilted. The Observer Human biology David Cox Sat 4 Jul 2020 12.00 EDT Share icons: Facebook, Twitter, email. 2,668 480 Does the key to anti-ageing lie in our bones? Photo: X-ray images of running skeletons on black background.
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Anecdotal Testimony “ My blood sugar level Dropped by 50 points! „ “ I have very high blood sugar level despite medications I am currently taking. In a fasted state in the morning, I usually get blood sugar level between 160-230 mg/dL. After taking AIC Therapy Mainteance to strengthen my bone for two weeks, I noticed that my blood sugar level was keep dropping. My fasted sugar level in mornings now dropped to 118-160 mg/dL level! Nothing could lower my sugar level this low. I am so excited and looking forward to experiencing more! Thank you.” Mrs. K., NY
Anecdotal Testimony “ My blood sugar level Dropped by 120 points! „ "May I also share my wife's experience with AIC : My wife is now 68 yrs old, 2 yrs ago she was diagnosed with stage 2 breast C.A. and had mastectomy of her right breast last 2017 in Medical Center. Tumor size was 10.5cm. She is also diabetic with blood sugar from 250 to 340 in spite of her taking Metformin, Dou and Ampalaya plus daily.
Anecdotal Testimony (continued) “After the surgery (total mastectomy of her right breast), the lady surgeon told my wife to have her chemo at another medical center the following week after we checked out from the Hospital. I and our daugther, J, did not agree with the doctor for the chemo treatment. Instead we went to Dr. E S. where she was given AIC to be taken 3 x daily. After 3 weeks she had her regular blood sugar test at home and to our surprise her blood sugar went down to 120 from 250 to 300 before taking AIC, and up to now her blood sugar is between 120 to 130 every day. The Most AMAZING RESULT AFTER 4 MONTHS OF TAKING AIC 3X DAILY, HER TUMOR MARKER TEST WAS BELOW 11.3 WHICH IS ALMOST "CANCER FREE" WITHOUT CHEMO and RADIATION treatments. She had her tumor marker test early this year and she is now CANCER FREE!!! and BLOOD SUGAR at 120 to 130 which is very normal for a 68 yr old! Thanks to AIC! THANKS TO GOD!!!"
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